Biomedical Imaging

Medical and biomedical imaging are disciplines necessary in virtually all fields of biomedical engineering. Developing technologies to visualize and model disease, injury, and even healthy tissue lie at the root of diagnosis and treatment.

Guohua Cao

Guohua CaoDr. Cao’s X-Ray Systems Lab aims at developing novel medical imaging technologies for biomedical and bioscientific discovery, radiological diagnosis, and medical intervention. The lab focuses on novel x-ray sources, detectors, and systems engineering. The research activities are interdisciplinary and translational, and interface between basic sciences, translational development, and clinical applications.

Location: Virginia Tech campus

Tom Diller

Tom DillerMeasurement of heat transfer has wide-ranging applications in biomedical engineering -- from thermal comfort to blood perfusion. Several different non-invasive thermal methods for perfusion measurement have been developed. Applications are being developed for quantification of peripheral vascular disease, burn severity, pressure ulcers, wound healing, and melanoma detection.

Location: Virginia Tech campus

Scott Gayzik

Scott GayzikI have a background in solid mechanics and mechanical engineering, which I have leveraged, in conjunction with my training as a biomedical engineer, to make advancements in the field of accelerative loading injury protection. My specific graduate training at VT&WFU revolved around the biomechanics of injury. While my strongest area is in computational biomechanics, my research encompasses projects touching on all aspects of civilian and military injury biomechanics, including projects in human model development and morphing, injury metric development, risk curve development, thermal burns and therapeutics, and the basic-science aspects of injury biomechanics.

Location: Wake Forest campus

Metin Gurcan

Metin GurcanThe qualitative analysis of histopathological and radiological images is time-consuming and subject to inter- and intra-reader variations. This affects the prediction of the clinical outcome in an undesirable way. As a result, we are developing image analysis systems for computer-assisted interpretations of these images to help pathologists and radiologists in their analysis of images. Our goal is to provide computational tools with which they can extract quantitative features useful for more objective and accurate detection, diagnosis, and prognosis. In addition, we are investigating high performance computational infrastructures to efficiently process these large images. The current systems developed in our Clinical Image Analysis (CIALAB) have provided promising results - both in terms of accuracy and also computational efficiency.

Location: Wake Forest campus

Bethany Kerr

Bethany KerrThe Kerr lab is focused on uncovering the mechanisms driving cancer metastasis with an emphasis on prostate cancer bone metastasis. Our goal is to discover new biomarkers capable of differentiating patients likely to progress to metastasis from those with indolent disease. Within the primary tumor, we study angiogenesis, extracellular matrix proteins, and cancer stem cells. In the circulation, we focus on platelets and disseminated tumor cells. We use live cell imaging, 3D cell culture systems, and in vivo fluorescent imaging among other methodologies to examine metastatic initiation and spread.

Location: Wake Forest campus

Paul Laurienti

Paul LaurientiWe use complexity theory and network science to understand normal and abnormal brain function. Current projects: Developing new methods to generate functional brain networks. Effects of alcohol on brain networks Effects of obesity, weight loss, and exercise in the aging brain Brain health in farmworkers exposed to pesticides and nicotine.

Location: Wake Forest campus

Steve Poelzing

Steve PoelzingWe have identified a number of cardiac associated mutations and mapped out the effects on multiple molecular pathways. Yet, many patients with mutations are indistinguishable from genotypically “normal” patients until they die suddenly. We study a new electrical pathway by which cardiac cells communicate and conceal disease causing mutations. to treat vascular-related diseases.

Location: Virginia Tech campus

Joel Stitzel

Joel StitzelComputational modeling of the human body, THUMS - Total Human Model for Safety, and GHBMC - Global Human Body Models Consortium. CIREN - Crash Injury Research and Engineering Network. Anthropometry and modeling of real-world injuries. Advanced automatic crash notification algorithms utilizing hospital and crash databases for trauma triage. iTAKL - Imaging, Telemetry, and Kinematic Modeling of instrumented youth and high school football teams with medical imaging to understand biomechanics of subconcussive head impact. Human injury biomechanics, computational modeling of the human body, the relationship between computational model-based metrics and criteria and real-world injury and disease. Current support from industry and government: DOT, NASA, NSF (REU), DOD, NIH.

Location: Wake Forest campus

Ashley Weaver

Ashley WeaverInjury biomechanics research focusing on the prevention, mitigation, and treatment of motor vehicle crash, military, and sporting injuries. Research interests include advanced automatic crash notification, human body and vehicle finite element modeling, and medical imaging analysis for anthropometry and bone quality characterization.

Location: Wake Forest campus

Jared Weis

Jared WeisThe overall theme of my research is concentrated in applying computational modeling and non-invasive imaging methodologies to explore the nature of soft-tissue mechanics in cancer and development, with an emphasis on driving clinical therapeutic interventions. Research focuses on the multi-disciplinary study of the multi-scale influences of mechanics in cancer progression and response to therapy, involving the development and validation of imaging-based mathematical modeling approaches to evaluate and parameterize biophysical properties of cancer and predict responsiveness to therapy.

Location: Wake Forest campus

Dawen Zhao

Dawen ZhaoDevelopment of theranostic agents for brain tumor diagnosis and treatment. Development of image-guided drug delivery system to cross the BBB to treat brain tumors.

Location: Wake Forest campus

Faculty with Related Interests

Affiliated Labs, Centers, and Institutes