Marissa Nichole Rylander, Ph.D.

Assistant Professor 
Department of Mechanical Engineering

VT/WFU School of Biomedical Engineering and Sciences
1880 Pratt Drive, RB XV (Mail Code 0493)
Blacksburg, VA  24061

Phone:  540-231-3134
Fax: 540-231-0970

E-mail: mnr@vt.edu
http://www.me.vt.edu/nrylander/


EDUCATION:

	B.S., University of Texas-Austin, Mechanical Engineering, 2000
	M.S., University of Texas-Austin, Mechanical Engineering, 2002
	Ph.D., University of Texas-Austin, Biomedical Engineering, 2005
	Postdoctoral Fellow, University of Texas-Austin, Institute for Computational Engineering and Science, 2005-2006

RESEARCH INTERESTS:

	Thermal therapy design for cancer treatment and cardiac preconditioning
	Nanotechnology for therapeutics and diagnostics
	Measurement and imaging of cellular and tissue protein expression
	Bioheat transfer modeling
	Controlled angiogenesis and Heat Shock Protein (HSP) expression in tumors and tissue engineered constructs

TEACHING INTERESTS:

	Heat/Bioheat Transfer
	Thermal Therapy Design

RECENT PUBLICATIONS:

	M. N. Rylander, Y. Feng, Y. Zhang, J. Bass, R. J. Stafford, J. Hazle, and K. R. Diller, 2006, “Optimizing HSP Expression in Prostate Cancer Laser Therapy Through Predictive Computational Models,’ Journal of Biomedical Optics, 11:4,  04111131-16. Diller, K.R. and Rylander, M.N., Bioheat Transfer Phenomena Expressed Across Multiple Length Scales, Proceedings 13th International Heat Transfer Conference, Sydney, 2006, KN-03, 1-15.
	J. T. Oden, K. R. Diller, C. Bajaj, J. C. Browne, J. Hazle, I. Babuska, J. Bass, L. Demkowicz, Y. Feng, D. Fuentes, S. Prudhomme, M. N. Rylander, R. J. Stafford, and Y. Zhang, “Development of a Computational Paradigm for Laser Treatment of Cancer,” conference paper for 6th World Congress on Computational Mechanics, California, July, 2006, Lecture Notes in Computer Science, 3993, 530-537.
	Y. Feng, M. N. Rylander, J. Bass, J.T. Oden, and K. R.  Diller, “Optimal Design of Laser Surgery for Cancer Treatment Through Nanoparticle-Mediated Hyperthermia Therapy,” conference paper for National Cancer Institute - Special Symposium on Nanotechnology for Cancer Prevention, Diagnosis, and Treatment, California, May 2005, NSTI-Nanotech. 1, 39-42.
	M. N. Rylander, Y. Feng, J. Bass, and K. R. Diller, 2005, “Thermally Induced Injury and Heat-Shock Protein Expression in Cells and Tissues,” Annals of New York Academy of Science, 1066, 222-242.
	M. N. Rylander, S. Wang, S. Aggarwal, and K. R. Diller, 2005, “Correlation of HSP 70 Expression and Cell Viability Following Thermal Stimulation of Bovine Aortic Endothelial Cells,” Journal of Biomechanical Engineering, 127, 751-757.
	M. N. Rylander, Y. Feng, J. Bass, and K. R. Diller, 2006, “HSP Expression and Damage Optimization Algorithm for Prostate Cancer Therapy Design,” Lasers in Surgery and Medicine, In review.
	M. N. Rylander, Y. Feng, and K. R. Diller, 2006, “Thermally Induced HSP27, HSP60, and HSP70 Expression Kinetics and Cell Viability in Normal and Cancerous Prostate Cells,” The Prostate, In review.
	S Wang, W. Xie, M. N. Rylander, P. W. Tucker, S. Aggarwal, and K. R. Diller, 2006, “HSP70 Kinetics Study by Continuous Observation of HSP-GFP Fusion Protein Expression on a Perfusion Heating Stage,” Biotechnology and Bioengineering, In review.