Joseph W. Freeman, Ph.D.

Assistant Professor
Biomedical Engineering

Virginia Tech
CRC Research Building 15, Room 1116
Blacksburg, VA  24061

Phone: 540-231-5686
E-mail: jwfreeman@vt.edu



Musculoskeletal Tissue Regeneration Lab

EDUCATION:

	B.S.E., Princeton University, Chemical Engineering, 1997
	Ph.D., Rutgers University, Biomedical Engineering, 2003

RESEARCH INTERESTS:

	Tissue Engineering
	Molecular Modeling
	Biomechanics
	Biomaterials

RECENT PUBLICATIONS:

	J. W. Freeman, M. D. Woods, C. T. Laurencin, Tissue Engineering of the Anterior Cruciate Ligament Using a Braid-Twist Scaffold Design”, Journal of Biomechanics.  2007;40 (9):2029-2036
	W. J. Landis, F. H. Silver, J. W. Freeman, “Collagen as a scaffold for biomimetic mineralization of vertebrate tissues”, J. Mater. Chem., 2006, 16, 1495
	C. T. Laurencin, J. W. Freeman, “Ligament Tissue Engineering: An Evolutionary Materials Science Approach”, Biomaterials. 2005 Dec;26 (36):7530-6.
	F. H. Silver, J. W. Freeman, G.Bradica, “Structure and Function of Ligaments, Tendons and Joint Capsule”. Chapter 2, Orthopedic Biology and Medicine Series:  Repair and Regeneration of Ligaments, Tendon and Capsule , Humana Press, July 2005.
	J. W. Freeman, F. H. Silver, M. D. Woods, C. T. Laurencin, “The Role of Type I Collagen Molecular Structure in Tendon Elastic Energy Storage” Proceedings:  Material Research Society Spring Symposium, Materials Research Society, 2005.
	J. W. Freeman, F. H. Silver, “The Effects of Prestrain and Collagen Fibril Alignment on In Vitro Mineralization of Self-Assembled Collagen Fibers” Connect Tissue Res. 2005;46 (2):107-15.
	H. H. Lu, J. A. Cooper, S. Manuel, J. W. Freeman, M. A. Attawia, F. K. Ko, C. T. Laurencin, “Anterior Cruciate Ligament Regeneration Using Braided Biodegradable Scaffolds: In Vitro Optimization Studies”,  Biomaterials. 2005 Aug;26 (23):4805-16.
	J. A. Cooper, H. H. Lu, F. K. Ko, J. W. Freeman, C. T. Laurencin, “Fiber-based tissue-engineered scaffold for ligament replacement: design considerations and in vitro evaluation”,  Biomaterials. 2005 May; 26 (13):1523-32.
	J. W. Freeman, F. H. Silver, “Analysis Of Mineral Deposition In Turkey Tendons And Self-Assembled Collagen Fibers Using Mechanical Techniques” Connect Tissue Res. 2004;45 (3):131-41.
	J. W. Freeman, F. H. Silver, “Elastic energy storage in unmineralized and mineralized extracellular matrices (ECMs): a comparison between molecular modeling and experimental measurements”, J Theor Biol. 2004 Aug 7; 229 (3):371-81.
	F. H. Silver, J. W. Freeman, and G. P. Seehra, "Collagen Self Assembly and the Development of Tendon Mechanical Properties", Journal of Biomechanics 2003 Oct; 36 (10): 1529-1553.
	F. H. Silver, J. W. Freeman, I. Horvath, and G.Bradica, “The Role of Collagen in Energy Storage and Dissipation in ECM” Proceedings: Protein-based Nanotechnology Satellite Meeting, 47th Annual Meeting, Biophysical Society, 2003.
	F. H. Silver, G. P, Seehra, and J. W. Freeman, and D. DeVore, “Viscoelastic Properties of Young and Old Human Dermis:  A Proposed Molecular Mechanism for Elastic Energy Storage in Collagen and Elastin." Journal of Applied Polymer Science 2002 Nov, 86 (8): 1978-85.
	F. H. Silver, J. W. Freeman, I. Horvath, and W. J. Landis, "Molecular Basis for Elastic Energy Storage In Mineralized Tendon", Biomacromolecules 2001 Sept; 2 (1): 750-756.
	F. H. Silver, J. W. Freeman, and D. DeVore, "Viscoelastic Properties of Human Skin and Processed Dermis", Skin Res Technol. 2001 Feb; 7 (1):18-23.

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