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Chenming (Mike) Zhang, Ph.D.
Associate Professor
Department of Biological Systems Engineering
Virginia Tech
210 Seitz Hall
Blacksburg, VA 24061
EDUCATION:
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B.S., University of Science and Technology Beijing, 1986 (Metallurgical Physical Chemistry)
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M.S., University of Science and Technology Beijing, China, 1991 (Metallurgical Physical Chemistry)
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M.S., Iowa State University, 1996 (Physical & Analytical Chemistry)
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Ph.D., Iowa State University, 1999 (Chemical Engineering)
RESEARCH INTERESTS:
Recombinant protein expression and purification from transgenic plant; protein characterization and structure-based drug design; edible vaccine development.
RECENT PUBLICATIONS:
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Matanin, B., Meng, X.J., and Zhang, C., 2007. Purification of the major envelop protein GP5 of porcine reproductive and respiratory syndrome virus (PRRSV) from native virions. Journal of Virological Methods. In press
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Holler, C. and Zhang, C., 2007. Purification of an acidic recombinant protein from transgenic tobacco. Biotechnology and Bioengineering. In press.
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Holler, C., Vaughan, D., and Zhang, C., 2007. Polyethyleneimine precipitation vs. anion exchange chromatography in fractionating recombinant b-glucuronidase from transgenic tobacco extract. Journal of Chromatography A. 1142:98-105.
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Zhang, C., Medina-Bolivar, F., Buswell, S., and Cramer, C. L., 2005. Purification and stabilization of ricin B from tobacco hairy root culture medium by aqueous two phase extraction. Journal of Biotechnology. 117(1): 39-48.
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Zhang, C. and Glatz, C. E., 2005. Applicability of the stoichiometric displacement model to description of the retention behavior of charged-fusion proteins during fast protein liquid chromatography. Journal of Chromatography A. 1069(1): 113-118.
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Buswell, S., Medina-Bolivar, F., Chen, Q., Van Cott, K., and Zhang, C., 2005. Expression of porcine prorelaxin in transgenic tobacco. Annals of the New York Academy of Sciences. 1041: 77-81.
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Zhang, C., Lillie, R., Cotter, J., and Vaughan, D., 2005. Lysozyme purification from tobacco extract by polyelectrolyte precipitation. Journal of Chromatography A. 1069 (1): 107-112.
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Menkhaus, T. J., Bai, Y., Zhang, C., Nikolov, Z. L., and C. E. Glatz, 2004. Considerations for the Recovery of Recombinant Proteins from Plants. (Review) Biotechnology Progress 20 (4): 1001-1014.
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Lindsay, M., Gil, G. C., Cadiz, A., Velander, W. H., Zhang, C., and Van Cott, K. E., 2004. Purification of recombinant DNA-derived Factor IX produced in transgenic pig milk and fractionation of active and inactive subpopulations. Journal of Chromatography A 1026 (1/2): 149-157.
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