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Jacquelyn S. Fetrow, Ph.D.
Reynolds Professor
Dept. of Physics and Computer Science
Wake Forest University
301 Olin Physical Lab (Physics)
234 West Hall (Computer Science)
Winston-Salem, NC 27157
336-758-4957
336-758-6142 (phys) or 7190 (cs) | fax
fetrowjs@wfu.edu
http://www.wfu.edu/~fetrowjs/
EDUCATION:
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BS, Biochemistry, Albright College, Reading PA
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Ph.D., Biological Chemistry, Penn State University College of Medicine, Hershey, PA
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Postdoctoral Fellowships: University of Rochester School of Medicine, Rochester, NY;
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Whitehead Institute for Biomedical Research (MIT), Boston, MA.
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TEACHING INTERESTS:
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Protein structure and function
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RESEARCH INTERESTS:
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Protein structure/function relationships
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Relationship between protein dynamics
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Protein function, and drug or inhibitor binding
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Structure-based drug discovery
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Systems biology and modeling of signal transduction pathways
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RECENT PUBLICATIONS:
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Salsbury Jr., F.R., Knutson, S.T., Poole, LB, and Fetrow, J.S. Functional Site Profiling and Electrostatic Analysis of Cysteines Modifiable to Cysteine Sulfenic Acid. Protein Sci. 2007. Accepted with revisions.
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Budiman, M.E., Knaggs, M.H., Fetrow, J.S., and Alexander, R.W. Using molecular dynamics to map interaction networks in an aminoacyl-tRNA synthetase. Proteins: Struct Funct Bioinform. Proteins. 2007 Aug 15;68(3):670-89.
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Knaggs, M.H., Salsbury, F.R., Edgell, M.H., Fetrow, J.S. Insights into CheY relaxation and relaxation derived from molecular dynamics simulations. Biophys J. 2007 Mar 15;92(6):2062-79. Epub 2006 Dec 15.
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Baxter SM, Day SW, Fetrow JS, Reisinger SJ. Scientific software development is not an oxymoron. PLoS Comput Biol. 2006 Sep 8;2(9):e87.
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Fetrow, J. S. Active site profiling to identify protein functional sites in sequences and structures. Current Protocols in Bioinformatics. (A.D. Baxevanis (chief editor); G.A. Petsko; L.D. Stein; G.D. Stormo; J.R. Yates III (guest editor); D.B. Davison (advisory editor); John Wiley and Sons, Inc. Unit 8.10, June 2006.
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Olex, A.L., John, D.J., Hiltbold, E.M., and Fetrow, J.S. Additional limitations of the clustering validation method figure of merit. Proceedings of the 45th ACM Southeast Regional Conference, Winston-Salem, NC. March 2007.
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Fetrow, J.S. and John, D.J. Bioinformatics and computing curriculum: A new model for interdisciplinary courses. Inroads--SIGSCE Bulletin. 2006. 38:185-190.
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Fetrow, J.S., Knutson, S.T. and Edgell, M.H. Mutations in α-helical solvent exposed sites of eglin c have long-range effects: evidence from molecular dynamics simulations. Proteins: Struct Funct Bioinform. 2006 May 1;63(2):356-72. [Epub 2005 Dec 9]
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Allen, E.E., Fetrow, J.S., Daniel, L.W., Thomas, S.J., John, D.J. Algebraic dependency models of protein signal transduction networks from time-series data. J. Theor. Biol. 2006 Jan 21;238(2):317-30. [Epub 2005 Jul 5]
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Huff, R. G., Bayram, E., Tan, H., Knutson, S.T., Knaggs, M.H., Richon, A.B., Santago II, P., and Fetrow, J.S. Chemical and Structural Diversity in Cyclooxygenase Protein Active Sites. Chemistry and Biodiversity. 2005. 2:1533-1552.
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