Jacquelyn S. Fetrow, Ph.D.

Reynolds Professor
Dept. of Physics and Computer Science

Wake Forest University
301 Olin Physical Lab (Physics)
234 West Hall (Computer Science)
Winston-Salem, NC 27157

Phone: 336-758-4957
Fax: 336-758-6142 (phys) or  7190 (cs)

Email: fetrowjs@wfu.edu
http://www.wfu.edu/~fetrowjs/

EDUCATION:

	BS, Biochemistry, Albright College, Reading PA
	Ph.D., Biological Chemistry, Penn State University College of Medicine, Hershey, PA
	Postdoctoral Fellowships: University of Rochester School of Medicine, Rochester, NY;
	Whitehead Institute for Biomedical Research (MIT), Boston, MA.

TEACHING INTERESTS:

	Bioinformatics
	Biochemistry
	Computational biophysics
	Protein structure and function

RESEARCH INTERESTS:

	Protein structure/function relationships
	Relationship between protein dynamics
	Protein function, and drug or inhibitor binding
	Structure-based drug discovery
	Systems biology and modeling of signal transduction pathways

RECENT PUBLICATIONS:

	Salsbury Jr., F.R., Knutson, S.T., Poole, LB, and Fetrow, J.S. Functional Site Profiling and Electrostatic Analysis of Cysteines Modifiable to Cysteine Sulfenic Acid. Protein Sci. 2007. Accepted with revisions.
	Budiman, M.E., Knaggs, M.H., Fetrow, J.S., and Alexander, R.W. Using molecular dynamics to map interaction networks in an aminoacyl-tRNA synthetase. Proteins: Struct Funct Bioinform. Proteins. 2007 Aug 15;68(3):670-89.
	Knaggs, M.H., Salsbury, F.R., Edgell, M.H., Fetrow, J.S. Insights into CheY relaxation and relaxation derived from molecular dynamics simulations. Biophys J. 2007 Mar 15;92(6):2062-79. Epub 2006 Dec 15.
	Baxter SM, Day SW, Fetrow JS, Reisinger SJ. Scientific software development is not an oxymoron. PLoS Comput Biol. 2006 Sep 8;2(9):e87.
	Fetrow, J. S.  Active site profiling to identify protein functional sites in sequences and structures.  Current Protocols in Bioinformatics. (A.D. Baxevanis (chief editor); G.A. Petsko; L.D. Stein; G.D. Stormo; J.R. Yates III (guest editor); D.B. Davison (advisory editor); John Wiley and Sons, Inc. Unit 8.10, June 2006.
	Olex, A.L., John, D.J., Hiltbold, E.M., and Fetrow, J.S. Additional limitations of the clustering validation method figure of merit. Proceedings of the 45th ACM Southeast Regional Conference, Winston-Salem, NC. March 2007.
	Fetrow, J.S. and John, D.J. Bioinformatics and computing curriculum: A new model for interdisciplinary courses. Inroads--SIGSCE Bulletin. 2006. 38:185-190.
	Fetrow, J.S., Knutson, S.T. and Edgell, M.H. Mutations in α-helical solvent exposed sites of eglin c have long-range effects: evidence from molecular dynamics simulations. Proteins: Struct Funct Bioinform. 2006 May 1;63(2):356-72. [Epub 2005 Dec 9]
	Allen, E.E., Fetrow, J.S., Daniel, L.W., Thomas, S.J., John, D.J. Algebraic dependency models of protein signal transduction networks from time-series data. J. Theor. Biol. 2006 Jan 21;238(2):317-30. [Epub 2005 Jul 5]
	Huff, R. G., Bayram, E., Tan, H., Knutson, S.T., Knaggs, M.H., Richon, A.B., Santago II, P., and Fetrow, J.S. Chemical and Structural Diversity in Cyclooxygenase Protein Active Sites. Chemistry and Biodiversity. 2005. 2:1533-1552.