Aaron M. Mohs, Ph.D.
Biomedical Engineering, Institute for Regenerative Medicine, Cancer Biology
Wake Forest University Health Sciences
Medical Center Boulevard
Winston-Salem, NC 27157
Phone: 336-713-1326 or 336-716-0488
- B.A., Chemistry, Saint John's University (Collegeville, MN)
- Ph.D., Pharmaceutics and Pharmaceutical Chemistry, University of Utah
- Postdoctoral Fellowship, Biomedical Engineering, Emory-Georgia Tech
- Image-guided surgery
- Minimally-invasive surgery
- Molecular imaging
- Multifunctional nanoparticles
- Pathway to Independence Award in Cancer Nanotechnology Research (K99/R00), Awarded by NIH/NCI (2010-current)
- Innovation of the Year (Integrated Imaging and Spectroscopy System for Image-Guided Surgery) - awarded by the Emory Office of Technology Transfer (2010)
- Emory-Ga. Tech Center for Cancer Nanotechnology Excellence Distinguished Fellowship (2006-2011)
- Wolf Prize - awarded to a University of Utah College of Pharmacy graduate student for excellence in teaching (2006)
- Jeffrey A. Fox Award - awarded to University of Utah, Pharmaceutics graduate student for dedication and service to department (2006)
- PhRMA Foundation Predoctoral Fellowship awarded by the PhRMA Foundation (2005)
- Mohs AM*, Mancini MC*, Provenzale JM, Singhal S, Leyland-Jones B, Wang MD, Nie S. (2010) Hand-held spectroscopic device for in vivo and intraoperative tumor detection: contrast enhancement, detection sensitivity, and tissue penetration. Anal. Chem. 82(21):9058-9065. *Denotes equal contribution.
- Provenzale JM, Mohs AM. (2010) Nanotechnology in neurology-current status and future possibilities. US Neurology 6(1):12-17.
- Mohs AM, Provenzale JM. (2010) Applications of nanotechnology to imaging and therapy of brain tumors. Neuroimag. Clin. N. Am. 20(3):283-292.
- Mohs AM, Duan HW, Kairdolf BA, Smith AM, Nie S. (2009) Proton-resistant quantum dots: stability in gastrointestinal fluids and implications for oral delivery of nanoparticle agents. Nano. Res. 2:500-508.
- Smith AM, Mohs AM, Nie S. (2009) Tuning the optical and electronic properties of semiconductor nanocrystals by lattice strain. Nat. Nanotech. 4(1):56-63.
- Feng Y, Jeong EK, Mohs AM, Emerson L, Lu ZR. (2008) Characterization of tumor angiogenesis with dynamic contrast-enhanced magnetic resonance imaging and biodegradable macromolecular contrast agents in mice. Magn. Reson. Med. 60(6):1347-1352.
- Smith AM, Duan HW, Mohs AM, Nie S. (2008) Bioconjugated quantum dots for in vivo molecular and cellular imaging. Adv. Drug. Deliv. Rev. 60(11):1226-1240.
- Mohs AM, Nguyen T, Jeong EK, Feng Y, Emerson LL, Zong Y, Parker DL, Lu ZR. (2007) Pegylation of Gd-DTPA cystine copolymers optimizes pharmacokinetics and tissue retention for magnetic resonance angiography. Magn. Reson. Med. 58(1):110-118.
- Mohs AM, Lu ZR. (2007) Gadolinium(III)-based blood pool contrast agents for magnetic resonance imaging: current status and clinical potential. Expert Opin. Drug. Deliv. 4(2):149-164.
- Zong Y, Guo J, Ke T, Mohs AM, Parker DL, Lu ZR. (2006) Effect of size and charge on pharmacokinetics and in vivo MRI contrast enhancement of biodegradable polydisulfide Gd(III) complexes. J. Control. Release 112:350-356.
- Lu ZR, Mohs AM, Zong Y, Feng Y. (2005) Polydisulfide Gd(III) chelates as biodegradable macromolecular magnetic resonance imaging contrast agents. Intl. J. Nanomed. 1:31-40.
- Mohs AM, Zong Y, Guo J, Parker DL, Lu ZR. (2005) PEG-g-poly(GdDTPA-co-L-cystine): effect of PEG chain length on in vivo contrast enhancement in MRI. Biomacromolecules 6:2305-2311.
- Zong Y, Wang X, Goodrich KC, Mohs AM, Parker DL, Lu ZR. (2005) Contrast-enhanced MRI with new biodegradable macromolecular Gd(III) complexes in tumor-bearing mice. Magn. Reson. Med. 53:835-842.
- Mohs AM, Wang X, Zong Y, Goodrich KC, Parker DL, Lu ZR. (2004) PEG-g-poly(GdDTPA-co-L- cystine): A biodegradable macromolecular blood pool contrast agent for MR imaging. Bioconj. Chem. 15:1424-1430.